Quasispecies: From Theory to Experimental Systems Current Topics in Microbiology and Immunology


<p>Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology.?</p>Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology. 

Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology. 

Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology.?</p>Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology. 

Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology. 

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Quasispecies: From Theory to Experimental Systems Current Topics in Microbiology and Immunology



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