![]() | Quasispecies: From Theory to Experimental Systems Current Topics in Microbiology and Immunology |
<p>Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology.?</p>Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology.
Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology. Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology.?</p>Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseaseevents.Fromaclinicalperspective,populationdynamicshighlightsimportantproblemsforviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology. Thisvolumebringstogetherrecentdevelopmentsinquasispeciestheoryextendedtovariableenvironmentsandpracticalapplicationsinelucidatingviraldynamicsandtreatmentdesigns.Inparticular,theexistenceofanerrorthresholdinruggedfitnesslandscapeshasopenedthewaytoanewantiviralstrategytermedlethalmutagenesis,whichisnowunderintensivetheoretical,experimentalandclinicalinvestigation.Assuchthebookexplainshowanunderstandingofquasispeciesdynamicswithininfectedorganismshasincreasedourknowledgeofviraldiseasecontrol,suchastheselectionofdrug-resistantmutantsthatoftenaccompaniestreatmentfailures,andsuggestsmeansofincreasingtheeffectivenessofantiviraltreatments.Thebookisintendedforstudentsandscientistsinterestedinbasicandappliedaspectsofbiophysics,chemistry,biology,evolutionandmedicalvirology. <p>画面が切り替わりますので、しばらくお待ち下さい。※切り替わらない場合は、こちらをクリックして下さい。
![]() | Quasispecies: From Theory to Experimental Systems Current Topics in Microbiology and Immunology |
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